Research group: Structural & Molecular VirologyGroup leader

Phone: +33 (0)4 91 16 41 28

Room: BM304

Publications

2023

2023
Combining DEVS simulation and ontological modeling for hierarchical analysis of the SARS-CoV-2 replication

Ali Ayadi, Claudia Frydman, Wissame Laddada, Isabelle Imbert, Cecilia Zanni-Merk, Lina Soualmia

SIMULATION: Transactions of The Society for Modeling and Simulation International (2023)10.1177/00375497231176085

2022

2022
Replication of the coronavirus genome: A paradox among positive-strand RNA viruses

Emeline Grellet, India l'Hôte, Adeline Goulet, Isabelle Imbert

Journal of Biological Chemistry 298 (2022)10.1016/j.jbc.2022.101923

2020

2020
The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation

Coralie Valle, Baptiste Martin, Francoise Debart, Jean-Jacques Vasseur, Isabelle Imbert, Bruno Canard, Bruno Coutard, Etienne Decroly

Journal of Virology 94:e00520-20 (2020)10.1128/JVI.00520-20

2018

2018
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA

Francois Ferron, Lorenzo Subissi, Ana Theresa Silveira de Morais, Nhung Thi Tuyet Le, Marion Sevajol, Laure Gluais, Etienne Decroly, Clemens Vonrhein, Gérard Bricogne, Bruno Canard, Isabelle Imbert

Proceedings of the National Academy of Sciences of the United States of America 115:E162-E171 (2018)10.1073/pnas.1718806115

2017

2017
Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

Rana Abdelnabi, Ana Theresa Silveira De Morais, Pieter Leyssen, Isabelle Imbert, Stéphanie Beaucourt, Hervé Blanc, Mathy Froeyen, Marco Vignuzzi, Bruno Canard, Johan Neyts, Leen Delang

Journal of Virology 91:e00487-17 (2017)10.1128/JVI.00487-17

2014

2014
Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

Mickaël Bouvet, Adrien Lugari, Clara C. Posthuma, Jessika C. Zevenhoven, Stéphanie Bernard, Stéphane Betzi, Isabelle Imbert, Bruno Canard, Jean-Claude Guillemot, Patrick Lécine, Susanne Pfefferle, Christian Drosten, Eric J. Snijder, Etienne Decroly, Xavier Morelli

Journal of Biological Chemistry 289:25783-25796 (2014)10.1074/jbc.M114.577353

2011

2011
Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex.

Claire Debarnot, Isabelle Imbert, Francois Ferron, Laure Gluais, Isabelle Varlet, Nicolas Papageorgiou, Mickaël Bouvet, Julien Lescar, Etienne Decroly, Bruno Canard

Acta crystallographica Section F : Structural biology communications [2014-...] 67:404-8 (2011)10.1107/S1744309111002867

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