2025
2025
Selection and optimization strategy for Rap1-targeting single-domain antibodies as platelet activation markers
Marie-Christine Alessi, Maxime Moulard, Daniele Boulay-Moine, Cyril Pons, Marielle Margier, Cléa Vessière, Marjorie Poggi, Theo Pigaglio, Francoise Dignat-George, Alain Roussel, Stéphane Burtey, Laurent Bonello, Patrick Chames, Remi Bonjean, Franck Peiretti
Research and Practice in Thrombosis and Haemostasis 10:103294 (2025)10.1016/j.rpth.2025.103294
2025
“French Phage Network” annual conference—eighth meeting report
Carole Armal, Charles-Adrien Arnaud, Emilie Cenraud, Youn Le Cras, Pierre-Alexandre Pastouriaux, Callypso Pellegri, Laurent Debarbieux
microLife 6:uqaf001 (2025)10.1093/femsml/uqaf001
2025
Mapping of Mycobacterial Enzymes Involved in Triacylglycerol Accumulation as Intrabacterial Lipid Inclusions Using Activity-Based Multitarget Inhibitor Probes
Romain Avellan, Jordan Lehoux, Thomas Francis, Tonia Dargham, Léa Celik, Alexandre Guy, Isabelle Poncin, Vanessa Point, Laurent Kremer, Thierry Durand, Stéphane Audebert, Luc Camoin, Christopher Spilling, Pierre Santucci, Céline Crauste, Stéphane Canaan, Jean-François Cavalier
ACS Infectious Diseases 11:1589-1605 (2025)10.1021/acsinfecdis.5c00127
2025
Characterization of strictly lytic phages infecting Oenococcus oeni from Merlot wines and proposal of a new genus
Yasma Barchi, Florencia Oviedo-Hernandez, Amel Chaïb, Cécile Philippe, Olivier Claisse, Christian Cambillau, Adeline Goulet, Claire Le Marrec
Microbiology Spectrum 13 (2025)10.1128/spectrum.02588-24
2025
Potency of all-D amino acid antimicrobial peptides derived from the bovine rumen microbiome on tuberculous and non-tuberculous mycobacteria
Céline Boidin-Wichlacz, Marc Maresca, Isabelle Correia, Olivier Lequin, Vanessa Point, Magali Casanova, Alexis Reinbold, Olga Iranzo, Sharon Huws, Priscille Brodin, Linda Oyama, Aurélie Tasiemski, Stéphane Canaan, Jean-François Cavalier
Current Research in Microbial Sciences 8:100395 (2025)10.1016/j.crmicr.2025.100395
2025
Bioactive Compounds Discovery from French Guiana Plant Extracts Through Antitubercular Screening and Molecular Networking
Célia Breaud, Clémentine Saunier, Béatrice Baghdikian, Fathi Mabrouki, Myriam Bertolotti, Mariana Royer, Pierre Silland, Marc Maresca, Eldar Garaev, Jean-François Cavalier, Stéphane Canaan, Sok-Siya Bun, Elnur Garayev
Plants 14:3028 (2025)10.3390/plants14193028
2025
Structural model of a bacterial focal adhesion complex
Christian Cambillau, Tâm Mignot
Communications Biology 8:119 (2025)10.1038/s42003-025-07550-w
2025
Cryo-EM structures of the E. coli Ton and Tol motor complexes
Herve Celia, Istvan Botos, Rodolfo Ghirlando, Denis Duché, Bridgette Beach, Roland Lloubes, Susan Buchanan
Nature Communications 16:5506 (2025)10.1038/s41467-025-61286-z
2025
How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation
Umberto Contaldo, Paolo Santucci, Alexandra Vergnes, Philippe Leone, Jérôme Becam, Frédéric Biaso, Marianne Ilbert, Benjamin Ezraty, Elisabeth Lojou, Ievgen Mazurenko
JACS Au 5:1833-1844 (2025)10.1021/jacsau.5c00076
2025
A proteomic and functional view of intrabacterial lipid inclusion biogenesis in mycobacteria
Tonia Dargham, John Jairo Aguilera-Correa, Romain Avellan, Ivy Mallick, Léa Celik, Pierre Santucci, Gaël Brasseur, Isabelle Poncin, Vanessa Point, Stéphane Audebert, Luc Camoin, Wassim Daher, Jean-François Cavalier, Laurent Kremer, Stéphane Canaan
mBio 16:e01475-24 (2025)10.1128/mbio.01475-24
2025
Crystal Digital PCR™ Enables Precise Quantification of Species Abundance in Microbial Mixtures
Louis Delecourt, Mila Reset, Lionel Bertaux, James Sturgis, Yann Denis, Marie-Thérèse Giudici-Orticoni, Magali Roger, Christophe Bordi
Microorganisms 13:2592 (2025)10.3390/microorganisms13112592
2025
Anionic Lipids Regulate the Light-Harvesting Complex 1-Reaction Center Photocycle in Purple Bacteria
Olivia Fiebig, Graham Schmidt, Neetu Singh Yadav, Dihao Wang, Muath Nairat, Helen Tang, Yi Ji, Valérie Prima, James N. Sturgis, Josh Vermaas, Dvir Harris, Gabriela Schlau-Cohen
Journal of the American Chemical Society (2025)10.1021/jacs.5c12301
2025
The polyamino‐isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi‐target inhibitors against the ESKAPEE bacterium Enterobacter cloacae
Emma Forest, Jordan Lehoux, Alexandre Guy, Thierry Durand, Stéphane Audebert, Luc Camoin, Christopher D Spilling, Céline Crauste, Stéphane Canaan, Jean Michel Brunel, Jean‐michel Bolla, Jean‐françois Cavalier
mLife 4:259-274 (2025)10.1002/mlf2.70014
2025
Synthesis and Anti-mycobacterial Activity of Novel Medium-chain β-Lactone Derivatives: A Multi-Target Strategy to combat Mycobacterium abscessus
Thomas Francis, Christina Dedaki, Phoebe Ananida-Dasenaki, Dimitra Bolka, Kanellos Albanis, Filippos Foteinakis, Julie Mezquida, Marie Hance, Alexandros Athanasoulis, Anna-Krinio Papagiorgou, Ioanna-Foteini Karampoula, George Georgitsis, Celia Jardin, Stéphane Audebert, Luc Camoin, Céline Crauste, Stéphane Canaan, Victoria Magrioti, Jean-François Cavalier
RSC Medicinal Chemistry (2025)10.1039/D5MD00102A
2025
Dasatinib overcomes AML cells resistant to BCL2 inhibition by degrading MCL1
Sylvain Garciaz, Camille Montersino, Maxence Bourgoin, Arnaud Jacquel, Rémy Castellano, Arnaud Guille, Max Chaffanet, François Bertucci, Marie‐anne Hospital, José Adélaïde, Patrick Auberger, Norbert Vey, Yves Collette
British Journal of Haematology 207:381-386 (2025)10.1111/bjh.20195
2025
Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in gram‐negative bacteria
Audrey Goman, Bérengère Ize, Katy Jeannot, Camille Pin, Delphine Payros, Cécile Goursat, Léa Ravon-Katossky, Kazunori Murase, Camille Chagneau, Hélène Revillet, Frédéric Taieb, Sophie Bleves, Laure David, Etienne Meunier, Priscilla Branchu, Eric Oswald
Journal of Extracellular Vesicles 14:e270032 (2025)10.1002/jev2.70032
2025
Predicted Structures of Ceduovirus Adhesion Devices Highlight Unique Architectures Reminiscent of Bacterial Secretion System VI
Adeline Goulet, Jennifer Mahony, Douwe van Sinderen, Christian Cambillau
Viruses 17:1261 (2025)10.3390/v17091261
2025
Two cysteines control Tse1 secretion by H1 ‐ T6SS in Pseudomonas aeruginosa
Marie Grandjean, Jean‐pierre Duneau, Edwige Garcin, Laetitia Houot, Olivier Bornet, Christophe Bordi, Latifa Elantak, Corinne Sebban-Kreuzer
Protein Science 34:e70226 (2025)10.1002/pro.70226
2025
Membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper
Elodie Lafargue, Jean-Pierre Duneau, Nicolas Buzhinsky, Pamela Ornelas, Alexandre Ortega, Varun Ravishankar, James Sturgis, Ignacio Casuso, Lucie Bergdoll
Communications Biology 8:936 (2025)10.1038/s42003-025-08311-5
2025
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms.
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci
FEBS Letters 599:1634-1648 (2025)10.1002/1873-3468.70023
2025
Structure of the T9SS PorKN ring complex reveals conformational plasticity based on the repurposed FGE fold
Xiangan Liu, John D Perpich, Liqiang Song, Christian Cambillau, Thierry Doan, Lei Zheng, Richard J Lamont, Eric Cascales, Bo Hu
mBio 16:e01799-25 (2025)10.1128/mbio.01799-25
2025
Isolation and structure elucidation of cell surface polysaccharides from Oenococcus oeni
Emmanuel Maes, Irina Sadovskaya, Nao Yamakawa, Adeline Goulet, Claire Le Marrec, Marie-Pierre Chapot-Chartier
Carbohydrate Research 552:109456 (2025)10.1016/j.carres.2025.109456
2025
Widespread deployment of the human CD38 ADP-ribosyl cyclase fold in antibacterial and anti-eukaryotic polymorphic toxins
Julius Martinkus, Laurent Terradot, Dukas Jurėnas, Eric Cascales
Journal of Biological Chemistry 110775 (2025)10.1016/j.jbc.2025.110775
2025
Lactococcal mobile genetic elements harbour a diverse phage defensome rich in restriction-modification systems
Brian Mcdonnell, Philip Kelleher, Alexey Fomenkov, Guillermo Ortiz Charneco, Keith Coughlan, Pascal Quénée, Saulius Kulakauskas, Christian Cambillau, Brian P Anton, Paul P. de Waal, Noël N. M. E. van Peij, Francesca Bottacini, Jennifer Mahony, Richard John Roberts, Douwe van Sinderen
Nucleic Acids Research 53:gkaf854 (2025)10.1093/nar/gkaf854
2025
The great phage escape: Activating and escaping lactococcal antiphage systems
Cas Mosterd, Andriana Grafakou, Guillermo Ortiz Charneco, Paul P de Waal, Irma M H van Rijswijck, Noël N M E van Peij, Christine Péchoux, Saulius Kulakauskas, Christian Cambillau, Jennifer Mahony, Douwe van Sinderen
Proceedings of the National Academy of Sciences of the United States of America 122:e2426508122 (2025)10.1073/pnas.2426508122
2025
Isolation of phages infecting the zoonotic pathogen Streptococcus suis reveals novel structural and genomic characteristics
Emmanuel Kuffour Osei, Reuben O’hea, Christian Cambillau, Ankita Athalye, Frank Hille, Charles M.A.P. Franz, Áine O’doherty, Margaret Wilson, Gemma G.R. Murray, Lucy A Weinert, Edgar Garcia Manzanilla, Jennifer Mahony, John G Kenny
Microbiological Research 296:128147 (2025)10.1016/j.micres.2025.128147
2025
Specialized shuttle proteins recognize Type IX secretion signals and target effectors to their final destinations in Flavobacterium johnsoniae
Maelle Paillat, Caterina Comas Hervada, Stéphane Audebert, Eric Cascales, Thierry Doan
Communications Biology 8:1566 (2025)10.1038/s42003-025-08926-8
2025
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
Eloïse Paulet, Julia Bartoli, Atakan Kabtan, Chloé Piras, Audrey Tempier, Eric Cascales, Julie Viala
FEBS Open Bio 15:1103-1112 (2025)10.1002/2211-5463.70038
2025
Venetoclax–Azacitidine Versus Azacitidine for the Treatment of Primary Refractory or First Relapsed Acute Myeloid Leukemia. An IPC ‐ DATAML ‐ MSKCC Retrospective Study
Cassandre Petit, Jules Higue, Ziyad Acheaibi, Julia Gilhodes, Marie‐anne Hospital, Raynier Devillier, Jan Bewersdorf, Aaron Goldberg, Arnaud Pigneux, Norbert Vey, Christian Récher, Maximilian Stahl, Sarah Bertoli, Pierre‐yves Dumas, Sylvain Garciaz
American Journal of Hematology 100:906-908 (2025)10.1002/ajh.27626
2025
Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi ‐mediated genetic repression systems
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci
FEBS Open Bio (2025)10.1002/2211-5463.70172
2025
An open chat with…Pierre Santucci: a testimonial on why we should engage with scientific societies and their journals
Pierre Santucci, Ioannis Tsagakis
FEBS Open Bio 15:894-897 (2025)10.1002/2211-5463.70045
2025
High‐Speed Atomic Force Microscopy Reveals the Dynamic Interplay of Membrane Proteins is Lipid‐Modulated
Eunji Shin, Yining Jiang, Batiste Thienpont, James N. Sturgis, Simon Scheuring
Small Science (2025)10.1002/smsc.202500258
2025
Pushing the Boundaries of Resolution in Solid-State Nuclear Magnetic Resonance of Biomolecules with 160 kHz Magic-Angle Spinning
Zhiyu Sun, Claire Ollier, Adrienn Rancz, Batiste Thienpont, Kristof Grohe, Lukas Becker, Armin Purea, Frank Engelke, Sebastian Wegner, James N. Sturgis, Tatyana Polenova, Tanguy Le Marchand, Guido Pintacuda
Journal of the American Chemical Society 147:19433-19437 (2025)10.1021/jacs.5c02466
2025
Lactococcal phage–host profiling through binding studies between cell wall polysaccharide types and Skunavirus receptor-binding proteins
Kelsey White, Giovanni Eraclio, Brian Mcdonnell, Gabriele Andrea Lugli, Tadhg Crowley, Marco Ventura, Federica Volonté, Christian Cambillau, Fabio Dal Bello, Jennifer Mahony, Douwe van Sinderen
Microbial Genomics 11:001395 (2025)10.1099/mgen.0.001395
2025
Diversity and functional characterization of HNH endonucleases encoded by lactococcal Skunavirus phages
Jun-Hyeok Yu, Christian Cambillau, Gabriele Andrea Lugli, Marco Ventura, Arjen Nauta, Jennifer Mahony, Douwe van Sinderen
Microbial Genomics 11:001548 (2025)10.1099/mgen.0.001548