Adeline Goulet
CRCN, CNRS
Publications
2022
2022
A structural discovery journey of streptococcal phages adhesion devices by AlphaFold2
Adeline Goulet, Raphaela Joos, Katherine Lavelle, Douwe van Sinderen, Jennifer Mahony, Christian Cambillau
Frontiers in Molecular Biosciences 9 (2022)10.3389/fmolb.2022.960325
2022
Exploring Structural Diversity among Adhesion Devices Encoded by Lactococcal P335 Phages with AlphaFold2
Adeline Goulet, Jennifer Mahony, Christian Cambillau, Douwe van Sinderen
Microorganisms 10:2278 (2022)10.3390/microorganisms10112278
2022
Present Impact of AlphaFold2 Revolution on Structural Biology, and an Illustration With the Structure Prediction of the Bacteriophage J-1 Host Adhesion Device
Adeline Goulet, Christian Cambillau
Frontiers in Molecular Biosciences 9:907452 (2022)10.3389/fmolb.2022.907452
2022
Structure Prediction and Analysis of Hepatitis E Virus Non-Structural Proteins from the Replication and Transcription Machinery by AlphaFold2
Adeline Goulet, Christian Cambillau, Alain Roussel, Isabelle Imbert
Viruses 14 (2022)10.3390/v14071537
2022
Replication of the coronavirus genome: A paradox among positive-strand RNA viruses
Emeline Grellet, India l'Hôte, Adeline Goulet, Isabelle Imbert
Journal of Biological Chemistry 298 (2022)10.1016/j.jbc.2022.101923
2022
A truncated anti-CRISPR protein prevents spacer acquisition but not interference
Cécile Philippe, Carlee Morency, Pier-Luc Plante, Edwige Zufferey, Rodrigo Achigar, Denise M Tremblay, Geneviève M Rousseau, Adeline Goulet, Sylvain Moineau
Nature Communications 13 (2022)10.1038/s41467-022-30310-x
2021
2021
Structure and Topology Prediction of Phage Adhesion Devices Using AlphaFold2: The Case of Two Oenococcus oeni Phages
Adeline Goulet, Christian Cambillau
Microorganisms 9:2151 (2021)10.3390/microorganisms9102151
2020
2020
Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9
Daniel Agudelo, Sophie Carter, Minja Velimirovic, Alexis Duringer, Jean-François Rivest, Sébastien Levesque, Jérémy Loehr, Mathilde Mouchiroud, Denis Cyr, Paula Waters, Mathieu Laplante, Sylvain Moineau, Adeline Goulet, Yannick Doyon
Genome Research 30:107-117 (2020)10.1101/gr.255414.119
2020
Conserved and Diverse Traits of Adhesion Devices from Siphoviridae Recognizing Proteinaceous or Saccharidic Receptors
Adeline Goulet, Silvia Spinelli, Jennifer Mahony, Christian Cambillau
Viruses 12 (2020)10.3390/v12050512
2020
Diversity of molecular mechanisms used by anti-CRISPR proteins: the tip of an iceberg?
Pierre Hardouin, Adeline Goulet
Biochemical Society Transactions 48:507-516 (2020)10.1042/BST20190638
2020
Revisiting the host adhesion determinants of Streptococcus thermophilus siphophages
Katherine Lavelle, Adeline Goulet, Brian Mcdonnell, Silvia Spinelli, Douwe Van Sinderen, Jennifer Mahony, Christian Cambillau
Microbial Biotechnology 13:1765-1779 (2020)10.1111/1751-7915.13593
2020
Wine phenolic compounds differently affect the host-killing activity of two lytic bacteriophages infecting the lactic acid bacterium oenococcus oeni
Cécile Philippe, Amel Chaib, Fety Jaomanjaka, Stéphanie Cluzet, Aurélie Lagarde, Patricia Ballestra, Alain Decendit, Melina Petrel, Olivier Claisse, Adeline Goulet, Christian C. Cambillau, Claire Le Marrec
Viruses 12:1-19 (2020)10.3390/v12111316
2020
Structural Insights into Lactococcal Siphophage p2 Baseplate Activation Mechanism
Silvia Spinelli, Denise Tremblay, Sylvain Moineau, Christian Cambillau, Adeline Goulet
Viruses 12 (2020)10.3390/v12080878
2019
2019
Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase
Claire Debarnot, Yoan Monneau, Veronique Roig-Zamboni, Vincent Delauzun, Christine Le Narvor, Emeline Richard, Jérôme Hénault, Adeline Goulet, Firas Fadel, Romain R Vivès, Bernard Priem, David Bonnaffé, Hugues Lortat-Jacob, Yves Bourne
Proceedings of the National Academy of Sciences of the United States of America 116:6760-6765 (2019)10.1073/pnas.1818333116
2019
Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6
Olivier Fuchsbauer, Paolo Swuec, Claire Zimberger, Beatrice Amigues, Sébastien Levesque, Daniel Agudelo, Alexis Duringer, Antonio Chaves-Sanjuan, Silvia Spinelli, Geneviève Rousseau, Minja Velimirovic, Martino Bolognesi, Alain Roussel, Christian C. Cambillau, Sylvain Moineau, Yannick Doyon, Adeline Goulet
Molecular Cell 76:922-937.e7 (2019)10.1016/j.molcel.2019.09.012
2018
2018
Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins
Alexander Hynes, Geneviève Rousseau, Daniel Agudelo, Adeline Goulet, Béatrice Amigues, Jeremy Loehr, Dennis Romero, Christophe Fremaux, Philippe Horvath, Yannick Doyon, Christian Cambillau, Sylvain S. Moineau
Nature Communications 9:2919 (2018)10.1038/s41467-018-05092-w
2017
2017
Toscana virus nucleoprotein oligomer organization observed in solution
Amal Baklouti, Adeline Goulet, Julie Lichiere, Bruno Canard, Remi Charrel, Francois Ferron, Bruno Coutard, Nicolas Papageorgiou
Acta crystallographica Section D : Structural biology [1993-...] 73:650-659 (2017)10.1107/S2059798317008774
2016
2016
Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism
Adeline Goulet, Mishan Britto, Syeda Rizvi, Ottilie von Loeffelholz, Carolyn Moores, Robert Cross
Proceedings of the National Academy of Sciences of the United States of America 113:E7483-E7489 (2016)10.1073/pnas.1611581113
2015
2015
RNA 1 and RNA 2 Genomic Segments of Chronic Bee Paralysis Virus Are Infectious and Induce Chronic Bee Paralysis Disease
Ibrahim Youssef, Frank Schurr, Adeline Goulet, Nicolas Cougoule, Magali Ribiere-Chabert, Herve Darbon, Richard Thiery, Eric Dubois
Journal of Immunology Research 2015:423493 (8 pages) (2015)10.1155/2015/423493
2014
2014
Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family
Adeline Goulet, Jennifer Major, Yonggun Jun, Steven Gross, Steven Rosenfeld, Carolyn Moores
Proceedings of the National Academy of Sciences of the United States of America 111:1837-1842 (2014)10.1073/pnas.1319848111
2013
2013
New Insights into the Mechanism of Force Generation by Kinesin-5 Molecular Motors
Adeline Goulet, Carolyn Moores, William Behnke-Parks, Charles Sindelar, Jennifer Major, Steven Rosenfeld
Journal of Biological Chemistry 304:419-466 (2013)10.1016/B978-0-12-407696-9.00008-7
2012
2012
Crystal Structure of ATVORF273, a New Fold for a Thermo- and Acido-Stable Protein from the Acidianus Two-Tailed Virus
Catarina Felisberto-Rodrigues, Stéphanie Blangy, Adeline Goulet, Gisle Vestergaard, Christian Cambillau, Roger Garrett, Miguel Ortiz-Lombardía
PLoS ONE 7:e45847 (2012)10.1371/journal.pone.0045847
2012
The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5
Adeline Goulet, William M Behnke-Parks, Charles V Sindelar, Jennifer Major, Steven S Rosenfeld, Carolyn A Moores
Journal of Biological Chemistry 287:44654-44666 (2012)10.1074/jbc.m112.404228
2011
2011
The Opening of the SPP1 Bacteriophage Tail, a Prevalent Mechanism in Gram-positive-infecting Siphophages
Adeline Goulet, Joséphine Lai-Kee-Him, David Veesler, Isabelle Auzat, Gautier Robin, Dale Shepherd, Alison Ashcroft, Eric Richard, Julie Lichière, Paulo Tavares, Christian Cambillau, Patrick Bron
Journal of Biological Chemistry 286:25397-25405 (2011)10.1074/jbc.M111.243360
2009
2009
Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage.
Adeline Goulet, Stéphanie Blangy, Peter Redder, David Prangishvili, Catarina Felisberto-Rodrigues, Patrick Forterre, Valérie Campanacci, Christian Cambillau
Proceedings of the National Academy of Sciences of the United States of America 106:21155-60 (2009)10.1073/pnas.0909893106
2009
The crystal structure of ORF14 from Sulfolobus islandicus filamentous virus
Adeline Goulet, Silvia Spinelli, Stéphanie Blangy, Herman van Tilbeurgh, Nicolas Leulliot, Tamara Basta, David Prangishvili, Christian Cambillau, Valérie Campanacci
Proteins - Structure, Function and Bioinformatics 76:1020-1022 (2009)10.1002/prot.22448
2009
The thermo- and acido-stable ORF-99 from the archaeal virus AFV1
Adeline Goulet, Silvia Spinelli, Stéphanie Blangy, Herman van Tilbeurgh, Nicolas Leulliot, Tamara Basta, David Prangishvili, Christian Cambillau, Valérie Campanacci
Protein Science 18:1316-1320 (2009)10.1002/pro.122
2006
2006
Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV)
Adeline Goulet, Silvia Spinelli, Sophie Porciero, Stéphanie Blangy, Roger Garrett, Herman van Tilbeurgh, Nicolas Leulliot, Tamara Basta, David Prangishvili, Christian Cambillau
Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62:884-886 (2006)10.1107/S1744309106029150