Research group: Pseudomonas aeruginosa pathogenicityGroup leader

Phone: +33 (0)4 91 16 44 51

Room: BM102

Publications

2020

2020
Bacterial injection machines: Evolutionary diverse but functionally convergent

Sophie Bleves, Jorge Galán, Matxalen Llosa

Cellular Microbiology e13157 (2020)10.1111/cmi.13157

2020
Editorial: Protein Export and Secretion Among Bacterial Pathogens

Thibault Sana, Romé Voulhoux, Denise Monack, Bérengère Ize, Sophie Bleves

Frontiers in Cellular and Infection Microbiology 9 (2020)10.3389/fcimb.2019.00473

2019

2019
A Type VI Secretion System trans- kingdom effector is required for the delivery of a novel antibacterial toxin in Pseudomonas aeruginosa

Benjamin Berni, Chantal Soscia, Sarah Djermoun, Bérengère Ize, Sophie Bleves

Frontiers in Microbiology (2019)10.3389/fmicb.2019.01218

2019
Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants

Preeti Garai, Laurence Berry, Malika Moussouni, Sophie Bleves, Anne-Béatrice Blanc-Potard

PLoS Pathogens 15:e1007812 (2019)10.1371/journal.ppat.1007812

2019
Differential modulation of Quorum-Sensing signaling through QslA in Pseudomonas

Thibault Gery Sana, Rodrigo Lomas, Maxime Rémi Gimenez, Aurélie Laubier, Chantal Soscia, Claire Chauvet, Ana Conesa, Romé Voulhoux, Bérengère Ize, Sophie Bleves

Journal of Bacteriology (2019)

2018

2018
United we stand, divided we fall

Sophie Bleves, Benjamin Berni

Nature Microbiology (2018)10.1038/s41564-018-0130-x

2018
Genome wide identification and experimental validation of Pseudomonas aeruginosa Tat substrates

Maxime Rémi Gimenez, Govind Chandra, Perrine van Overvelt, Romé Voulhoux, Sophie Bleves, Bérengère Ize

Scientific Reports 8:11950 (2018)10.1038/s41598-018-30393-x

2017

2017
Pseudomonas aeruginosa zinc uptake in chelating environment is primarily mediated by the metallophore pseudopaline

Sebastien Lhospice, Nicolas Gomez, Laurent Ouerdane, Catherine Brutesco, Ghassan Ghssein, Christine Hajjar, Ahmed Liratni, Shuanglong Wang, Pierre Richaud, Sophie Bleves, Geneviève Ball, Elise Borezée-Durant, Ryszard Lobinski, David Pignol, Pascal Arnoux, Romé Voulhoux

Scientific Reports 7:1-10 (2017)10.1038/s41598-017-16765-9

2016

2016
Game of Trans-Kingdom Effectors

Sophie Bleves

Trends in Microbiology 24:773-774 (2016)10.1016/j.tim.2016.08.002

2016
Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas aeruginosa.

Paulo Vinicius da Mata Madeira, Samira Zouhir, Pauline Basso, David Neves, Aurélie Laubier, Richard Salacha, Sophie Bleves, Eric Faudry, Carlos Contreras-Martel, Andréa Dessen

Journal of Molecular Biology 428:1790-803 (2016)10.1016/j.jmb.2016.03.012

2016
The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting.

Thibault G Sana, Benjamin Berni, Sophie Bleves

Frontiers in Cellular and Infection Microbiology 6:61 (2016)10.3389/fcimb.2016.00061

2015

2015
A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens

Claudine Belon, Chantal Soscia, Audrey Bernut, Aurélie Laubier, Sophie Bleves, Anne-Béatrice Blanc-Potard

PLoS Pathogens 11:e1004969 (2015)10.1371/journal.ppat.1004969

2015
Intracellular phase for an extracellular bacterial pathogen: MgtC shows the way

Audrey Bernut, Claudine Belon, Chantal Soscia, Sophie Bleves, Anne-Béatrice Blanc-Potard

Microbial Cell 2:353-355 (2015)10.15698/mic2015.09.227

2015
Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network

Thibault G. Sana, Christoph Baumann, Andreas Merdes, Chantal Soscia, Thomas Rattei, Abderrahman Hachani, Cerith Jones, Keiryn L. Bennett, Alain Filloux, Giulio Superti-Furga, Romé Voulhoux, Sophie Bleves

mBio 6 (2015)

2015
Genome-wide Screen of Pseudomonas aeruginosa in Saccharomyces cerevisiae Identifies New Virulence Factors.

Rafat Zrieq, Thibault G Sana, Sandra Vergin, Steve Garvis, Irina Volfson, Sophie Bleves, Romé Voulhoux, Johannes H Hegemann

Frontiers in Cellular and Infection Microbiology 5:81 (2015)10.3389/fcimb.2015.00081

2014

2014
HoPaCI-DB: host-Pseudomonas and Coxiella interaction database.

Sophie Bleves, Irmtraud Dunger, Mathias C Walter, Dimitrios Frangoulidis, Gabi Kastenmüller, Romé Voulhoux, Andreas Ruepp

Nucleic Acids Research 42:D671-6 (2014)10.1093/nar/gkt925

2014
The target cell genus does not matter.

Sophie Bleves, Thibault G Sana, Romé Voulhoux

Trends Microbiol. 22:304-6 (2014)10.1016/j.tim.2014.04.011

2014
Gene transfer: conjugation.

Thibault G Sana, Aurélie Laubier, Sophie Bleves

Methods in Molecular Biology 1149:17-22 (2014)10.1007/978-1-4939-0473-0_3

2013

2013
Divergent control of two type VI secretion systems by RpoN in Pseudomonas aeruginosa

Thibault G Sana, Chantal Soscia, Céline M Tonglet, Steve Garvis, Sophie Bleves

PLoS ONE 8:e76030 (2013)10.1371/journal.pone.0076030

2012

2012
The second type VI secretion system of Pseudomonas aeruginosa strain PAO1 is regulated by quorum sensing and Fur and modulates internalization in epithelial cells.

Thibault G Sana, Abderrahman Hachani, Iwona Bucior, Chantal Soscia, Steve Garvis, Elise Termine, Joanne Engel, Alain Filloux, Sophie Bleves

Journal of Biological Chemistry 287:27095-105 (2012)10.1074/jbc.M112.376368

2011

2011
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.

Abderrahman Hachani, Nadine S Lossi, Alexander Hamilton, Cerith Jones, Sophie Bleves, David Albesa-Jové, Alain Filloux

Journal of Biological Chemistry 286:12317-27 (2011)10.1074/jbc.M110.193045

2011
Role of fimV in type II secretion system-dependent protein secretion of Pseudomonas aeruginosa on solid medium.

Gérard P F Michel, Anthony Aguzzi, Geneviève Ball, Chantal Soscia, Sophie Bleves, Romé Voulhoux

Microbiology (Reading, Engl.) 157:1945-54 (2011)10.1099/mic.0.045849-0

2010

2010
The Pseudomonas aeruginosa patatin-like protein PlpD is the archetype of a novel Type V secretion system

R. Salacha, F. Kovacic, Céline Brochier-Armanet, S. Wilhelm, J. Tommassen, A. Filloux, R. Voulhoux, Sophie Bleves

Environmental Microbiology 12:1498-512 (2010)

2006

2006
Multiple sensors control reciprocal expression of Pseudomonas aeruginosa ezgulatory RNA and virulence genes.

Isabelle Ventre, Al Goodman, Isabelle Vallet-Gely, Perrine Vasseur, Chantal Soscia, Sören Molin, Sophie Bleves, Andrée Lazdunski, Steve Lory, Alain Filloux

Proceedings of the National Academy of Sciences of the United States of America 103:171-176 (2006)

1999

1999
Assembly of XcpR in the Cytoplasmic Membrane Is Required for Extracellular Protein Secretion in Pseudomonas aeruginosa

Genevieve Ball, Virginie Chapon, Sophie Bleves, Gérard Michel, Marc Bally

Journal of Bacteriology 181:382-388 (1999)

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