Stéphane Canaan
DR1, CNRS
Research group: Lipolysis & Bacterial PathogenicityGroup leader
Phone: +33 4 91 16 40 93
Room: BM311
Publications
2025
2025
Mapping of Mycobacterial Enzymes Involved in Triacylglycerol Accumulation as Intrabacterial Lipid Inclusions Using Activity-Based Multitarget Inhibitor Probes
Romain Avellan, Jordan Lehoux, Thomas Francis, Tonia Dargham, Léa Celik, Alexandre Guy, Isabelle Poncin, Vanessa Point, Laurent Kremer, Thierry Durand, Stéphane Audebert, Luc Camoin, Christopher Spilling, Pierre Santucci, Céline Crauste, Stéphane Canaan, Jean-François Cavalier
ACS Infectious Diseases 11:1589-1605 (2025)10.1021/acsinfecdis.5c00127
2025
Potency of all-D amino acid antimicrobial peptides derived from the bovine rumen microbiome on tuberculous and non-tuberculous mycobacteria
Céline Boidin-Wichlacz, Marc Maresca, Isabelle Correia, Olivier Lequin, Vanessa Point, Magali Casanova, Alexis Reinbold, Olga Iranzo, Sharon Huws, Priscille Brodin, Linda Oyama, Aurélie Tasiemski, Stéphane Canaan, Jean-François Cavalier
Current Research in Microbial Sciences 8:100395 (2025)10.1016/j.crmicr.2025.100395
2025
A proteomic and functional view of intrabacterial lipid inclusion biogenesis in mycobacteria
Tonia Dargham, John Jairo Aguilera-Correa, Romain Avellan, Ivy Mallick, Léa Celik, Pierre Santucci, Gael Brasseur, Isabelle Poncin, Vanessa Point, Stéphane Audebert, Luc Camoin, Wassim Daher, Jean-François Cavalier, Laurent Kremer, Stéphane Canaan
mBio 16:e01475-24 (2025)10.1128/mbio.01475-24
2025
The polyamino‐isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi‐target inhibitors against the ESKAPEE bacterium Enterobacter cloacae
Emma Forest, Jordan Lehoux, Alexandre Guy, Thierry Durand, Stéphane Audebert, Luc Camoin, Christopher D Spilling, Céline Crauste, Stéphane Canaan, Jean Michel Brunel, Jean‐michel Bolla, Jean‐françois Cavalier
mLife 4:259-274 (2025)10.1002/mlf2.70014
2025
Synthesis and Anti-mycobacterial Activity of Novel Medium-chain β-Lactone Derivatives: A Multi-Target Strategy to combat Mycobacterium abscessus
Thomas Francis, Christina Dedaki, Phoebe Ananida-Dasenaki, Dimitra Bolka, Kanellos Albanis, Filippos Foteinakis, Julie Mezquida, Marie Hance, Alexandros Athanasoulis, Anna-Krinio Papagiorgou, Ioanna-Foteini Karampoula, George Georgitsis, Celia Jardin, Stéphane Audebert, Luc Camoin, Céline Crauste, Stéphane Canaan, Victoria Magrioti, Jean-François Cavalier
RSC Medicinal Chemistry (2025)10.1039/D5MD00102A
2025
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms.
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci
FEBS Letters (2025)10.1002/1873-3468.70023
2024
2024
A dTDP-L-Rhamnose 4-epimerase required for glycopeptidolipid biosynthesis in Mycobacterium abscessus
John Jairo Aguilera-Correa, Fangyu Wei, Louis-David Leclercq, Yara Tasrini, Edukondalu Mullapudi, Wassim Daher, Kazuki Nakajima, Stéphane Canaan, Jean-Louis Herrmann, Matthias Wilmanns, Yann Guérardel, Liuqing Wen, Laurent Kremer
Journal of Biological Chemistry 107852 (2024)10.1016/j.jbc.2024.107852
2024
Promising antibacterial efficacy of arenicin peptides against the emerging opportunistic pathogen Mycobacterium abscessus
Magali Casanova, Marc Maresca, Isabelle Poncin, Vanessa Point, Hamza Olleik, Céline Boidin-Wichlacz, Aurélie Tasiemski, Kamel Mabrouk, Jean-François Cavalier, Stéphane Canaan
Journal of Biomedical Science 31:18 (2024)10.1186/s12929-024-01007-8
2024
Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities
Attilio Di Maio, Hamza Olleik, Elise Courvoisier-Dezord, Sophie Guillier, Fabienne Neulat-Ripoll, Romain Haudecoeur, Jean-Michel Bolla, Magali Casanova, Jean-François Cavalier, Stéphane Canaan, Valérie Pique, Yolande Charmasson, Elias Baydoun, Akram Hijazi, Josette Perrier, Marc Maresca, Maxime Robin
Antibiotics 13:300 (2024)10.3390/antibiotics13040300
2024
Antitubercular potential and p H ‐driven mode of action of salicylic acid derivatives
Janïs Laudouze, Thomas Francis, Emma Forest, Frédérique Mies, Jean‐michel Bolla, Céline Crauste, Stéphane Canaan, Vadim Shlyonsky, Pierre Santucci, Jean‐françois Cavalier
FEBS Open Bio (2024)10.1002/2211-5463.13944
2024
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria
Janïs Laudouze, Vanessa Point, Wafaa Achache, Céline Crauste, Stéphane Canaan, Pierre Santucci
FEBS Letters (2024)10.1002/1873-3468.15071
2024
Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus
Morgane Sarrazin, Isabelle Poncin, Patrick Fourquet, Stéphane Audebert, Luc Camoin, Yann Denis, Pierre Santucci, Christopher D Spilling, Laurent Kremer, Vincent Le Moigne, Jean-Louis Herrmann, Jean-François Cavalier, Stéphane Canaan
Journal of Biomedical Science 31:103 (2024)10.1186/s12929-024-01091-w
2023
2023
Evaluation of the Efficiency of Random and Diblock Methacrylate-Based Amphiphilic Cationic Polymers against Major Bacterial Pathogens Associated with Cystic Fibrosis
Magali Casanova, Hamza Olleik, Slim Hdiouech, Clarisse Roblin, Jean-François Cavalier, Vanessa Point, Katy Jeannot, Baptiste Caron, Josette Perrier, Siméon Charriau, Mickael Lafond, Yohann Guillaneuf, Stéphane Canaan, Catherine Lefay, Marc Maresca
Antibiotics 12:120 (2023)10.3390/antibiotics12010120
2023
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis
Tonia Dargham, Ivy Mallick, Laurent Kremer, Pierre Santucci, Stéphane Canaan
FEBS Open Bio 13:2306-2323 (2023)10.1002/2211-5463.13721
2023
Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model
Thi Thu Hang Le, Christine Kellenberger, Marie Boyer, Pierre Santucci, Nicolas Flaugnatti, Eric Cascales, Alain Roussel, Stéphane Canaan, Laure Journet, Christian Cambillau
International Journal of Molecular Sciences 24:1740 (2023)10.3390/ijms24021740
2022
2022
Early life oxytocin treatment improves thermo-sensory reactivity and maternal behavior in neonates lacking the autism-associated gene Magel2
Laura Caccialupi da Prato, Ugo Zayan, Dina Abdallah, Vanessa Point, Fabienne Schaller, Emilie Pallesi-Pocachard, Aurélie Montheil, Stéphane Canaan, Jean-Luc Gaiarsa, Françoise Muscatelli, Valéry Matarazzo
Neuropsychopharmacology (2022)10.1038/s41386-022-01313-5
2022
Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives
Vasiliki Mavrikaki, Alexandros Pagonis, Isabelle Poncin, Ivy Mallick, Stéphane Canaan, Victoria Magrioti, Jean-François Cavalier
Bioorganic and Medicinal Chemistry Letters 64:128692 (2022)10.1016/j.bmcl.2022.128692
2022
Synthesis and Biological Characterization of Fluorescent Cyclipostins and Cyclophostin Analogues: New Insights for the Diagnosis of Mycobacterial-Related Diseases
Morgane Sarrazin, Benjamin Martin, Romain Avellan, Giri Raj Gnawali, Isabelle Poncin, Hugo Le Guenno, Christopher Spilling, Jean-François Cavalier, Stéphane Canaan
ACS Infectious Diseases (2022)10.1021/acsinfecdis.2c00448
2021
2021
Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?
Ivy Mallick, Pierre Santucci, Isabelle Poncin, Vanessa Point, Laurent Kremer, Jean-François Cavalier, Stéphane Canaan
FEMS Microbiology Reviews (2021)10.1093/femsre/fuab029
2021
Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone
Marie Robbe-Saule, Mélanie Foulon, Isabelle Poncin, Lucille Esnault, Hugo Varet, Rachel Legendre, Alban Besnard, Anna E Grzegorzewicz, Mary Jackson, Stéphane Canaan, Laurent Marsollier, Estelle Marion
Virulence 12:1438-1451 (2021)10.1080/21505594.2021.1929749
2020
2020
Lipolytic enzymes inhibitors: A new way for antibacterial drugs discovery
Jean-François Cavalier, Christopher D Spilling, Thierry Durand, Luc Camoin, Stéphane Canaan
European Journal of Medicinal Chemistry 112908 (2020)10.1016/j.ejmech.2020.112908
2020
Structural basis for loading and inhibition of a bacterial T6 SS phospholipase effector by the VgrG spike
Nicolas Flaugnatti, Chiara Rapisarda, Martial Rey, Solène G Beauvois, Viet Anh Nguyen, Stéphane Canaan, Eric Durand, Julia Chamot‐rooke, E. Cascales, Rémi Fronzes, Laure Journet
EMBO Journal 39:e104129 (2020)10.15252/embj.2019104129
2020
A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential
Vincent Le Moigne, Anne-Laure Roux, Aude Jobart-Malfait, Landry Blanc, Karima Chaoui, Odile Burlet-Schiltz, Jean-Louis Gaillard, Stéphane Canaan, Jérôme Nigou, Jean-Louis Herrmann
Frontiers in Cellular and Infection Microbiology 10 (2020)10.3389/fcimb.2020.00432
2020
Dissecting the antibacterial activity of oxadiazolone-core derivatives against Mycobacterium abscessus
Abdeldjalil Madani, Ivy Mallick, Alexandre Guy, Céline Crauste, Thierry Durand, Patrick Fourquet, Stéphane Audebert, Luc Camoin, Stéphane Canaan, Jean-François Cavalier
PLoS ONE 15:e0238178 (2020)10.1371/journal.pone.0238178
2019
2019
Haloarcula sebkhae sp. nov., an extremely halophilic archaeon from Algerian hypersaline environment
Hélène Barreteau, Manon Vandervennet, Laura Guedon, Vanessa Point, Stéphane Canaan, Sylvie Rebuffat, Jean Peduzzi, Alyssa Carré-Mlouka
International Journal of Systematic and Evolutionary Microbiology 69 (2019)10.1099/ijsem.0.003211
2019
Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of Mycobacterium abscessus
Abdeldjalil Madani, Jeremy Ridenour, Benjamin Martin, Rishi Paudel, Anosha Abdul Basir, Vincent Le Moigne, Jean-Louis Herrmann, Stéphane Audebert, Luc Camoin, Laurent Kremer, Christopher D Spilling, Stéphane Canaan, Jean-François Cavalier
ACS Infectious Diseases (2019)10.1021/acsinfecdis.9b00172
2019
Worms’ Antimicrobial Peptides
Bruno Renato, Marc Maresca, Stéphane Canaan, Jean-François Cavalier, Kamel Mabrouk, Céline Boidin-Wichlacz, Hamza Olleik, Daniela Zeppilli, Priscille Brodin, François Massol, Didier Jollivet, Sacha Jung, Aurélie Tasiemski
Marine drugs 17:512 (2019)10.3390/md17090512
2019
Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains
Pierre Santucci, Nabil Smichi, Sadia Diomandé, Isabelle Poncin, Vanessa Point, Hélène Gaussier, Jean-François Cavalier, Laurent Kremer, Stéphane Canaan
FEBS Journal (2019)10.1111/febs.14864
2019
Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria
Pierre Santucci, Matt Johansen, Vanessa Point, Isabelle Poncin, Albertus Viljoen, Jean-François Cavalier, Laurent Kremer, Stéphane Canaan
Scientific Reports 9 (2019)10.1038/s41598-019-45164-5
2019
Synthesis of Long-Chain β-Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria
Pierre Santucci, Christina Dedaki, Alexandros Athanasoulis, Laura Gallorini, Anaïs Munoz, Stéphane Canaan, Jean-François Cavalier, Victoria Magrioti
ChemMedChem 14:349-358 (2019)10.1002/cmdc.201800720
2019
Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility
Dong Yang, Guy Vandenbussche, Didier Vertommen, Damien Evrard, Romany Abskharon, Jean-François Cavalier, Gilles Berger, Stéphane Canaan, Mohammad Shahneawz Khan, Sheng Zeng, Alexandre Wohlkonig, Martine Prévost, Patrice Soumillion, Véronique Fontaine
FEBS Letters (2019)10.1002/1873-3468.13555
2018
2018
Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis
Phuong Chi Nguyen, van Son Nguyen, Benjamin Martin, Patrick Fourquet, Luc Camoin, Chistopher Spilling, Jean-François Cavalier, Christian Cambillau, Stéphane Canaan
Journal of Molecular Biology 430:5129-5136 (2018)10.1016/j.jmb.2018.09.017
2018
Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
Phuong Chi Nguyen, Vincent Delorme, Anaïs Benarouche, Alexandre Guy, Valérie Landry, Stéphane Audebert, Matthieu Pophillat, Luc Camoin, Céline Crauste, Jean-Marie Galano, Thierry Durand, Priscille Brodin, Stéphane Canaan, Jean-François Cavalier
Bioorganic Chemistry 81:414-424 (2018)10.1016/j.bioorg.2018.08.025
2018
Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases
Phuong Nguyen, Abdeldjalil Madani, Pierre Santucci, Benjamin Martin, Rishi R Paudel, Sandrine Delattre, Jean-Louis Herrmann, Christopher D Spilling, Laurent Kremer, Jean-François Cavalier, Stéphane Canaan
International Journal of Antimicrobial Agents (2018)10.1016/j.ijantimicag.2017.12.001
2018
The potent effect of mycolactone on lipid membranes
Milène Nitenberg, Anaïs Benarouche, Ofélia Maniti, Estelle Marion, Laurent L Marsollier, Julie Géan, Erick J Dufourc, Jean-François Cavalier, Stéphane Canaan, Agnès P Girard-Egrot
PLoS Pathogens 14:e1006814 (e-collection 2018 jan) (2018)10.1371/journal.ppat.1006814
2018
B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections
Wendy Rénier, Arnaud Bourdin, Pierre-Alain Rubbo, Marianne Peries, Luc Dedieu, Sophie Bendriss, Laurent Kremer, Stéphane Canaan, Dominique Terru, Sylvain Godreuil, Nicolas Nagot, Philippe van de Perre, Edouard Tuaillon
PLoS ONE 13:e0196470 (2018)10.1371/journal.pone.0196470
2018
Delineating the Physiological Roles of the PE and Catalytic Domains of LipY in Lipid Consumption in Mycobacterium-Infected Foamy Macrophages
Pierre Santucci, Sadia Diomandé, Isabelle Poncin, Laetitia Alibaud, Albertus Viljoen, Laurent Kremer, Chantal de Chastellier, Stéphane Canaan
Infection and Immunity 86 (2018)10.1128/IAI.00394-18
2018
LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling
Pierre Santucci, Vanessa Point, Isabelle Poncin, Alexandre Guy, Céline Crauste, Carole Serveau-Avesque, Jean-Marie Galano, Chistopher d. Spilling, Jean-François Cavalier, Stéphane Canaan
Bioscience Reports 38:BSR20181953 (2018)10.1042/BSR20181953
2018
Lipid Droplets Breakdown: Adipose Triglyceride Lipase Leads the Way
Pierre Santucci, Stéphane Canaan
Current Protein and Peptide Science 19:1131-1133 (2018)10.2174/1389203719666180809143000
2018
Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo
Albertus Viljoen, Matthias Richard, Phuong Chi Nguyen, Patrick Fourquet, Luc Camoin, Rishi R. Paudal, Giri R Gnawali, Christopher D Spilling, Jean-François Cavalier, Stéphane Canaan, Mickaël Blaise, Laurent Kremer
Journal of Biological Chemistry 293:2755-2769 (2018)10.1074/jbc.RA117.000760
2017
2017
Mycobacterium canettii Infection of Adipose Tissues
Feriel Bouzid, Fabienne Bregeon, Isabelle Poncin, Pascal Weber, Michel Drancourt, Stéphane Canaan
Frontiers in Cellular and Infection Microbiology 7:189-189 (2017)10.3389/fcimb.2017.00189
2017
Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis
Phuong Chi Nguyen, Vincent Delorme, Anaïs Benarouche, Benjamin Martin, Rishi Paudel, Giri R Gnawali, Abdeldjalil Madani, Rémy N Puppo, Valérie Landry, Laurent Kremer, Priscille Brodin, Christopher D Spilling, Jean-François Cavalier, Stéphane Canaan
Scientific Reports 7:11751 (2017)10.1038/s41598-017-11843-4
2017
Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm
Julien Parra, Julien Marcoux, Isabelle Poncin, Stéphane Canaan, Jean Louis Herrmann, Jérôme Nigou, Odile Burlet-Schiltz, Michel Rivière
Scientific Reports 7:43682 (2017)10.1038/srep43682
2016
2016
Smooth Tubercle Bacilli: Neglected Opportunistic Tropical Pathogens
Aboubaker Djaltou, Bouzid Feriel, Stéphane Canaan, Michel Drancourt
Frontiers in Public Health 283 (2016)10.3389/fpubh.2015.00283
2016
A phospholipase A 1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery
Nicolas Flaugnatti, Thi Thu Hang Le, Stéphane Canaan, Marie-Stéphanie Aschtgen, Vân Nguyên, Stephanie Blangy, Christine Kellenberger, Alain Roussel, Christian Cambillau, E. Cascales, Laure Journet
Molecular Microbiology 99:1099-1118 (2016)10.1111/mmi.13292
2016
Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens
Martine Gilleron, Marco Lepore, Emilie Layre, Diane Cala-De paepe, Naila Mebarek, James a. Shayman, Stéphane Canaan, Lucia Mori, Frédéric Carrière, Germain Puzo, Gennaro De libero
Cell Chemical Biology 23:1147-1156 (2016)10.1016/j.chembiol.2016.07.021
2016
Experimental Evolution of Mycobacterium tuberculosis in Human Macrophages Results in Low-Frequency Mutations Not Associated with Selective Advantage
V Guerrini, Subbian Satheshkumar, P. Santucci, Stéphane Canaan, Ml Gennaro, G. Pozzi
PLoS ONE e0167989 (2016)
2016
Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis
Pierre Santucci, Eerie Bouzid, Nabil Smichi, Isabelle Poncin, Laurent Kremer, Chantal de Chastellier, Michel Drancourt, Stéphane Canaan
Frontiers in Cellular and Infection Microbiology 6:122 (2016)10.3389/fcimb.2016.00122
2016
New lipase assay using Pomegranate oil coating in microtiter plates
S Ulker,, C Placidi,, V Point,, Stéphane Canaan, B. Gadenne, Carole Serveau-Avesque, Frédéric Carrière, Jean-François Cavalier
Biochimie 110-118 (2016)
2015
2015
Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: the Mycobacterium abscessus model
Vincent Le Moigne, Martin Rottman, Céline Goulard, Benoît Barteau, Isabelle Poncin, N Soismier, Stéphane Canaan, Bruno Pitard, Jl Gaillard, Jl Herrmann
Vaccine 33:2118-2124 (2015)10.1016/j.vaccine.2015.03.030
2014
2014
Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification
Vincent Delormea, Brigitt Raux, Rémy Puppo, Julien Leclaire, Sylvain Marc, Pavan-Kumar Kamarajugadda, Gérard Buono, Frédéric Fotiadu, Stéphane Canaan, Frédéric Carrière
Biochimie 107:124-134 (2014)10.1016/j.biochi.2014.07.015
2013
2013
Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis
Luc Dedieu, Carole Serveau-Avesque, Stéphane Canaan
PLoS ONE 8:e66913 (2013)10.1371/journal.pone.0066913
2013
Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research
Luc Dedieu, C. Serveau-Avesque, L. Kremer, Stéphane Canaan
Biochimie 95:66-73 (2013)10.1016/j.biochi.2012.07.008
2012
2012
MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth
Vincent Delorme, Sadia V. Diomandé, Luc Dedieu, Jean-François Cavalier, Fredéric Carrière, Laurent Kremer, Julien Leclaire, Frédéric Fotiadu, Stéphane Canaan
PLoS ONE 7:e46493 (2012)10.1371/journal.pone.0046493
2011
2011
Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis
Belinda Brust, Mélanie Lecoufle, Edouard Tuaillon, Luc Dedieu, Stéphane Canaan, Viviane Valverde, Laurent Kremer
PLoS ONE 6:e25078 (2011)10.1371/journal.pone.0025078
2011
Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies.
Cynthia Palmieri-Thiers, Jean-Christophe Alberti, Stéphane Canaan, Virginie Brunini, Claude Gambotti, Félix Tomi, Ernst H Oliw, Liliane Berti, Jacques Maury
Archives of Biochemistry and Biophysics 509:82-9 (2011)10.1016/j.abb.2011.02.008
2010
2010
Two cutinase-like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function.
Mathieu Schué, Damien Maurin, Rabeb Dhouib, Jean-Claude Bakala N'Goma, Vincent Delorme, Gérard Lambeau, Frédéric Carrière, Stéphane Canaan
FASEB Journal 24:1893-903 (2010)10.1096/fj.09-144766
2009
2009
A lipoxygenase with dual positional specificity is expressed in olives (Olea europaea L.) during ripening
Cynthia Palmieri-Thiers, Stéphane Canaan, Virginie Brunini, Vannina Lorenzi, Félix Tomi, Jean-Luc Desseyn, Ulrike Garscha, Ernst H Oliw, Liliane Berti, Jacques Maury
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1791:339-346 (2009)10.1016/j.bbalip.2009.02.012
2009
A lipoxygenase with dual positional specificity is expressed in olives (Olea europaea L.) during ripening.
Cynthia Palmieri-Thiers, Stéphane Canaan, Virginie Brunini, Vannina Lorenzi, Félix Tomi, Jean-Luc Desseyn, Ulrike Garscha, Ernst H Oliw, Liliane Berti, Jacques Maury
Biochimica et Biophysica Acta - Molecular Cell Research 1791:339-46 (2009)10.1016/j.bbalip.2009.02.012
2008
2008
A genomic search approach to identify esterases in Propionibacterium freudenreichii involved in the formation of flavour in Emmental cheese
Julien Dherbecourt, Hélène Falentin, Stéphane Canaan, Anne Thierry
Microbial Cell Factories 7:1-14 (2008)10.1186/1475-2859-7-16
2007
2007
Gene overexpression and biochemical characterization of the biotechnologically relevant chlorogenic acid hydrolase from Aspergillus niger
Isabelle Benoit, Michèle Asther, Yves Bourne, David Navarro, Stéphane Canaan, Laurence Lesage-Meessen, Marga Herweijer, Pedro M Coutinho, Marcel M. Asther, Eric Record
Applied and Environmental Microbiology 73:5624-5632 (2007)10.1128/AEM.00374-07
2007
Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids
Karen Côtes, Rabeb Dhouib, Isabelle Douchet, Henri Chahinian, Alain de Caro, Frédéric Carrière, Stéphane Canaan
Biochemical Journal 408:417-427 (2007)10.1042/BJ20070745
2006
2006
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity
M. Rouault, L.D. Rash, P. Escoubas, E. Boilard, J. Bollinger, B. Lomonte, T. Maurin, C. Guillaume, Stéphane Canaan, C. Deregnaucourt, J. Schrevel, A. Doglio, J.M. Gutierrez, M. Lazdunski, M. H. Gelb, G. Lambeau
Biochemistry 45:5800-5816 (2006)
2006
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis
Gerlind Sulzenbacher, Stéphane Canaan, Yann Bordat, Olivier Neyrolles, Gustavo Stadthagen, Véronique Roig-Zamboni, Jean Rauzier, Damien Maurin, Françoise Laval, Mamadou Daffé, Christian Cambillau, Brigitte Gicquel, Yves Bourne, Mary Jackson
EMBO Journal (2006)10.1038/sj.emboj.7601048
2005
2005
Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis
Stéphane Canaan, Gerlind Sulzenbacher, Véronique Roig-Zamboni, Loréna Scappuccini-Calvo, Frédéric Frassinetti, Damien Maurin, Christian Cambillau, Yves Bourne, Christian Griesinger
FEBS Letters (2005)10.1016/j.febslet.2004.11.069
2003
2003
Medium-Scale Structural Genomics: Strategies for Protein Expression and Crystallization
Renaud Vincentelli, Christophe Bignon, Arnaud Gruez, Stéphane Canaan, Gerlind Sulzenbacher, Mariella Tegoni, Rie Campanacci, Christian Cambillau
Accounts of Chemical Research (2003)10.1021/ar010130s