Research group: Dynamics and Assembly of membrane proteinsGroup leader

Phone: +33 (0)4 91 16 41 27

Room: IM109

Research Interests

I am interested in developing an interdisciplinary approach to the study of membrane proteininteractions. In particular I have developed in the group an approach that combines molecularbiology and biochemistry with modeling, imagery, and spectroscopy. We use this multidisciplinary approach to study several different systems, notably bacterial photosynthetic membranes, the E. colimembranes and single trans­membrane helix proteins such as tyrosine kinase associated receptors.

Publications

2020

2020
Comparison of the Energy-Transfer Rates in Structural and Spectral Variants of the B800–850 Complex from Purple Bacteria

Ashley Tong, Olivia Fiebig, Muath Nairat, Dvir Harris, Marcel Giansily, Aurélia Chenu, James Sturgis, Gabriela Schlau-Cohen

Journal of Physical Chemistry B 124:1460-1469 (2020)10.1021/acs.jpcb.9b11899

2020
High-speed atomic force microscopy highlights new molecular mechanism of daptomycin action

Francesca Zuttion, Adai Colom, Stefan Matile, Denes Farago, Frédérique Pompeo, Janos Kokavecz, Anne Galinier, James Sturgis, Ignacio Casuso

Nature Communications 11 (2020)10.1038/s41467-020-19710-z

2019

2019
The lipid environment of Escherichia coli Aquaporin Z

Victoria Schmidt, Marlon Sidore, Chérine Bechara, Jean-Pierre Duneau, James Sturgis

Biochimica et Biophysica Acta:Biomembranes 1861:431-440 (2019)10.1016/j.bbamem.2018.10.017

2018

2018
Out-of-Equilibrium Collective Oscillation as Phonon Condensation in a Model Protein

Ilaria Nardecchia, Jeremie Torres, Mathias Lechelon, Valeria Giliberti, Michele Ortolani, Philippe Nouvel, Matteo Gori, Yoann Meriguet, Irene Donato, Jordane Preto, Luca Varani, James Sturgis, Marco Pettini

Physical Review X 8:031061 (2018)10.1103/physrevx.8.031061

2018
Modifying styrene-maleic acid co-polymer for studying lipid nanodiscs

Victoria Schmidt, James Sturgis

Biochimica et Biophysica Acta:Biomembranes 1860:777-783 (2018)10.1016/j.bbamem.2017.12.012

2017

2017
Lipid perturbation by membrane proteins and the lipophobic effect

James Sturgis, Jean-Pierre Duneau, Jonathan Khao

Biochimica et Biophysica Acta:Biomembranes 1859:126-134 (2017)10.1016/j.bbamem.2016.10.014

2016

2016
Lipid Environment of Aquaporin Z

Schmidt Victoria, Sidore Marlon, Carrière Fredéric, Duneau Jean-Pierre, James Sturgis

Biophysical Journal 110:252a-253a (2016)10.1016/j.bpj.2015.11.1389

2015

2015
The E.coli Aquaporin Z interface : a puzzle?

Victoria Schmidt, Pierre Hubert, James Sturgis

Eur. Biophys. J. 44:S217 (2015)

2014

2014
Transmembrane Recognition of the Semaphorin Co-Receptors Neuropilin 1 and Plexin A1 : Coarse-Grained Simulations

Samia Aci-Sèche, Paul Sawma, Pierre Hubert, James Sturgis, Dominique Bagnard, Laurent Jacob, Monique Genest, Norbert Garnier

PLoS ONE 9:e97779 (2014)10.1371/journal.pone.0097779

2014
Ultrafast excited state processes in Roseobacter denitrificans antennae: comparison of isolated complexes and native membranes.

Marco Ferretti, Katia Duquesne, James Sturgis, Rienk Grondelle

Physical Chemistry Chemical Physics 16:26059-66 (2014)10.1039/c4cp02986k

2014
Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.

Paul Sawma, Lise Roth, Cécile Blanchard, Dominique Bagnard, Gérard Crémel, Emmanuelle Bouveret, Jean-Pierre Duneau, James Sturgis, Pierre Hubert

Journal of Molecular Biology 426:4099-111 (2014)10.1016/j.jmb.2014.10.007

2014
The architecture of Rhodobacter sphaeroides chromatophores

Simon Scheuring, Reinat Nevo, Lu-Ning Liu, Stéphanie Mangenot, Dana Charuvi, Thomas Boudier, Valerie Prima, Pierre Hubert, James Sturgis, Ziv Reich

Biochimica biophysica acta (BBA) - Bioenergetics 1837:1263-1270 (2014)10.1016/j.bbabio.2014.03.011

2014
Destabilizing Aquaporin Z Assembly: Effects on Structure, Function and Dynamics

Victoria Schmidt, Pierre Hubert, Valerie Prima, James Sturgis

Biophysical Journal 108:499a-500a (2014)

2013

2013
Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells.

Gilles Breuzard, Pierre Hubert, Roqiya Nouar, Tiphany De Bessa, François Devred, Pascale Barbier, James Sturgis, Vincent Peyrot

Journal of Cell Science 126:2810-9 (2013)10.1242/jcs.120832

2013

2012

2012
Structural properties of the tubular appendage spinae from marine bacterium Roseobacter sp. strain YSCB.

A Bernadac, L-F Wu, C-L Santini, C Vidaud, James Sturgis, N Menguy, P Bergam, C Nicoletti, T Xiao

Scientific Reports 2:950 (2012)10.1038/srep00950

2012
Complete Lateral and Angular Diffusion and Protein-Protein Interaction Description of a Membrane Protein

Ignacio Casuso, Jean-Pierre Duneau, Mohamed Chami, Perrine Paul-Gilloteaux, Mohamed Husain, Jonathan Khao, Henning Stahlberg, James Sturgis, Simon Scheuring

Biophysical Journal 102:413a-414a (2012)10.1016/j.bpj.2011.11.2261

2012
Characterization of the motion of membrane proteins using high-speed atomic force microscopy

Ignacio Casuso, Jonathan Khao, Mohamed Chami, Perrine Paul-Gilloteaux, Mohamed Husain, Jean-Pierre Duneau, Henning Stahlberg, James Sturgis, Simon Scheuring

Nature Nanotechnology 525-529 (2012)10.1038/nnano.2012.109

2012
Draft genome sequence of the purple photosynthetic bacterium Phaeospirillum molischianum DSM120, a particularly versatile bacterium.

K Duquesne, Valérie Prima, B Ji, Z Rouy, C Médigue, E Talla, James Sturgis

Journal of Bacteriology 194:3559-60 (2012)10.1128/JB.00605-12

2011

2011
Molecular origins and consequences of High-800 LH2 in Roseobacter denitrificans.

Katia Duquesne, Cecile Blanchard, James Sturgis

Biochemistry 50:6723-9 (2011)10.1021/bi200538j

2011
Structure of a protein-detergent complex: the balance between detergent cohesion and binding.

Jonathan Khao, Jaime Arce-Lopera, James Sturgis, Jean-Pierre Duneau

Eur. Biophys. J. 40:1143-55 (2011)10.1007/s00249-011-0745-9

2011
Native architecture of the photosynthetic membrane from Rhodobacter veldkampii.

Lu-Ning Liu, James Sturgis, Simon Scheuring

Journal of Structural Biology 173:138-45 (2011)10.1016/j.jsb.2010.08.010

2011
Antagonistic regulation of dgkA and plsB genes of phospholipid synthesis by multiple stress responses in Escherichia coli.

Astrid Wahl, Laetitia My, Romain Dumoulin, James Sturgis, Emmanuelle Bouveret

Mol. Microbiol. 80:1260-75 (2011)10.1111/j.1365-2958.2011.07641.x

2009

2009
High-resolution architecture of the outer membrane of the Gram-negative bacteria Roseobacter denitrificans.

Szymon Jarosławski, Katia Duquesne, James Sturgis, Simon Scheuring

Molecular Microbiology 74:1211-1222 (2009)10.1111/j.1365-2958.2009.06926.x

2007

2007
Rows of ATP Synthase Dimers in Native Mitochondrial Inner Membranes

Nikolay Buzhynskyy, Pierre Sens, Valérie Prima, James Sturgis, Simon Scheuring

Biophysical Journal 93:2870-2876 (2007)10.1529/biophysj.107.109728

2006

2006
Confined diffusion in tubular structures analyzed by fluorescence correlation spectroscopy on a mirror

E. Etienne, P.-F. Lenne, James Sturgis, H. Rigneault

Applied optics 45:4497-4507 (2006)10.1364/AO.45.004497

2006
The photosynthetic apparatus of Rhodopseudomonas palustris: Structures and organization.

Simon Scheuring, Rui Pedro Goncalves, Valérie Prima, James Sturgis

Journal of Molecular Biology in press:in press (2006)

2001

2001

2000

2000
2000
1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein.

Jean-Marie Peloponese, C. Gregoire, S Opi, E Esquieu, James Sturgis, E Lebrun, E. Meurs, C Collette, D Olive, M Aubertin, M Witvrow, C Pannecouque, E de Clercq, Cedric Bailly, J. Lebreton, E. Loret

Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie 323:883-94 (2000)10.1016/S0764-4469(00)01228-2

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